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KMID : 0616120110420020195
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Korean Journal of Pharmacognosy
2011 Volume.42 No. 2 p.195 ~ p.200
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Biological Activities of the Water Extract and its Fractions from Taraxacum coreanum Nakai
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Lee Kyoung-In
Im Do-Youn
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Abstract
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In this study, we investigated on antioxidative activity, tyrosinase inhibitory activity and nitric oxide(NO) production inhibitory activity in the hot water extract of Taraxacum coreanum and its fractions. The total polyphenol and flavonoid contents of the extract were found to be 65.42 mg/g and 9.83 mg/g, respectively. And the total polyphenol and flavonoid contents of the ethyl acetate fraction were found to be 168.23 mg/g and 31.92 mg/g, respectively. In DPPH radical scavenging ability, values of the ethyl acetate and butanol fraction were exhibited 64.65 and 277.42 , respectively. Moreover, ethyl acetate fraction showed higher inhibitory activity than other samples in tyrosinase inhibitory activity. In NO production inhibitory activity, the extract and its fractions showed NO production inhibitory effect. Especially, the ethyl acetate, chloroform and butanol fraction was exhibited higher NO production inhibitory activity than other samples. As a result, the ethyl acetate and butanol fraction from the water extract of T. coreanum could be applicable to functional materials for skin-related fields.
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KEYWORD
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Taraxacum coreanum, Anti-oxidant, Tyrosinase, Nitric oxide
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